Figure 1
Comparison of demographic data and clinical factors between patients with SARA ≥15 and SARA <15
| Data or factor, n (%) | SARA ≥15 (n = 15) | SARA <15 (n = 9) | P |
|---|---|---|---|
| SCA1 | 7 (47) | 6 (67) | |
| MJD (SCA3) | 8 (53) | 3 (33) | 0.34 |
| Male | 7 (47) | 5 (56) | 0.67 |
| Female | 8 (53) | 4 (44) | |
| Family history of SCA | 14 (93) | 7 (78) | |
| No family history | 1 (7) | 2 (22) | 0.27 |
| Medical diseases† | 7 (47) | 3 (33) | |
| No medical disease | 8 (53) | 6 (67) | 0.52 |
| Onset age ≥35 years | 9 (60) | 5 (56) | |
| Onset age <35 years | 6 (40) | 4 (44) | 0.83 |
| Body weight ≥60 kg | 8 (53) | 3 (33) | |
| Body weight <60 kg | 7 (47) | 6 (67) | 0.34 |
| Smoking | 5 (33) | 4 (44) | |
| Nonsmoking | 10 (67) | 5 (56) | 0.59 |
| Alcohol drinking | 7 (47) | 7 (78) | |
| Nonalcohol drinking | 8 (53) | 2 (22) | 0.14 |
| Head injury | 1 (7) | 1 (11) | 0.70 |
| No history of head injury | 14 (93) | 8 (89) |
Characteristics of spinocerebellar ataxia types in Buriram province, northeast Thailand
| Characteristic, n (%) | SCA1 | MJD (SCA3) | P |
|---|---|---|---|
| Cases (n) | 13 | 11 | |
| Sex | |||
| Male | 5 (39) | 7 (64) | 0.41 |
| Female | 8 (61) | 4 (36) | |
| Mean age of onset, years (range) | 37.0 (18–56) | 38.6 (25–59) | 0.28 |
| Positive family history | 10 (77) | 11 (100) | 0.22 |
| Clinical features | |||
| Slow saccade | 9 (69) | 9 (82) | 0.65 |
| Upward gaze paresis* | 3 (23) | 9 (82) | 0.012 |
| Horizontal nystagmus* | 3 (23) | 10 (91) | 0.001 |
| Vertical nystagmus | 1 (8) | 3 (27) | 0.30 |
| Pale optic disc | 0 | 0 | |
| Hyperreflexia | 11 (85) | 8 (73) | 0.63 |
| Babinski sign | 1 (8) | 2 (18) | 0.58 |
| Areflexia | 1 (8) | 3 (27) | 0.30 |
| Sensory impairment | 2 (15) | 5 (46) | 0.18 |
| Parkinsonism | 2 (15) | 1 (9) | >0.99 |