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Exploring the association between glucose-6-phosphate dehydrogenase deficiency and color blindness in Southeast Asia Cover

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Exploring the association between glucose-6-phosphate dehydrogenase deficiency and color blindness in Southeast Asia

Asian Biomedicine

Volume 11 (2017): Issue 4 (August 2017)

By: Ingfar Soontarawirat, Mallika Imwong, Charles J. Woodrow, Chalisa Louicharoen Cheepsunthorn, Nicholas P.J. Day, Richard Paul and Pratap Singhasivanon

Open Access

|Mar 2018

Figures & tables

Figures & Tables

Extent of homozygosity flanking the G6PD487A (Mahidol) allele over a 2.4-Mb region (based on Louicharoen et al. [7]). Positions of the 30 genotyped SNPs used to assess homozygosity are tagged by red arrows, and the positions of the Mahidol variant SNP and the SNP within the opsin locus are shown with orange arrows

Table 1

Distribution of 186 male participants in terms of color blindness and G6PD deficiency genotype

	G6PD deficient (n = 37)	G6PD normal (n = 149)
Normal color vision	36 (97.3%)	139 (93.3%)
	(34 Mahidol, 2 Viengchan)
Red-green color blind	1 (2.7%)	9 (6.0%)
	(Mahidol)
Total color blindness	0 (0%)	1 (0.7%)

Table 2

Haplotypes for 60 male participants G6PD Mahidol^487G<A and rs1573656 (opsin locus) according to color vision status

	G6PD Mahidol^487G<A	rs1573656 (G<A)	N
Normal color vision	G	G	20
	G	A	22
	A	G	14
Red–green color blind	G	G	3
Total color blindness	G	A	1

Articles in this issue

DOI: https://doi.org/10.1515/abm-2018-0009 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415

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Language: English

Page range: 365 - 370

Published on: Mar 21, 2018

Published by: Chulalongkorn University

In partnership with: Paradigm Publishing Services

Keywords:

chromosome Xq28,

color blindness,

linkage disequilibrium

Related subjects:

Assistive professions, nursing,

Basic medical science,

Basic medical science, other,

Clinical medicine,

Clinical medicine, other

© 2018 Ingfar Soontarawirat, Mallika Imwong, Charles J. Woodrow, Chalisa Louicharoen Cheepsunthorn, Nicholas P.J. Day, Richard Paul, Pratap Singhasivanon, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 11 (2017): Issue 4 (August 2017)

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