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Exploring the association between glucose-6-phosphate dehydrogenase deficiency and color blindness in Southeast Asia Cover

Exploring the association between glucose-6-phosphate dehydrogenase deficiency and color blindness in Southeast Asia

Open Access
|Mar 2018

Figures & Tables

Figure 1

Extent of homozygosity flanking the G6PD487A (Mahidol) allele over a 2.4-Mb region (based on Louicharoen et al. [7]). Positions of the 30 genotyped SNPs used to assess homozygosity are tagged by red arrows, and the positions of the Mahidol variant SNP and the SNP within the opsin locus are shown with orange arrows
Extent of homozygosity flanking the G6PD487A (Mahidol) allele over a 2.4-Mb region (based on Louicharoen et al. [7]). Positions of the 30 genotyped SNPs used to assess homozygosity are tagged by red arrows, and the positions of the Mahidol variant SNP and the SNP within the opsin locus are shown with orange arrows

Distribution of 186 male participants in terms of color blindness and G6PD deficiency genotype

G6PD deficient (n = 37)G6PD normal (n = 149)
Normal color vision36 (97.3%)139 (93.3%)
(34 Mahidol, 2 Viengchan)
Red-green color blind1 (2.7%)9 (6.0%)
(Mahidol)
Total color blindness0 (0%)1 (0.7%)

Haplotypes for 60 male participants G6PD Mahidol487G
G6PD Mahidol487G<Ars1573656 (G<A)N
Normal color visionGG20
GA22
AG14
Red–green color blindGG3
Total color blindnessGA1

DOI: https://doi.org/10.1515/abm-2018-0009 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 365 - 370
Published on: Mar 21, 2018
Published by: Chulalongkorn University
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2018 Ingfar Soontarawirat, Mallika Imwong, Charles J. Woodrow, Chalisa Louicharoen Cheepsunthorn, Nicholas P.J. Day, Richard Paul, Pratap Singhasivanon, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.