History of Heart Transplant: Setting the Stage

Farhan Ishaq; Ashrith Guha

doi:10.14797/mdcvj.1579

History of Heart Transplant: Setting the Stage

Methodist DeBakey Cardiovascular Journal

Volume 21 (2025): Issue 3

By: Farhan Ishaq and Ashrith Guha

Open Access

|May 2025

Abstract

Heart transplantation is a marvel of modern medicine for patients with end-stage heart failure. Decades of research and surgical innovation have overcome challenges in immunology, organ preservation, and patient care. From the earliest heart transplants on canines and primates, the field evolved through immunosuppressive therapies, development of the bioptome for endomyocardial biopsy and, recently, the use of cell free DNA and molecular microscopy for assessing rejection. Newer developments in organ preservation systems and transport systems bring remarkable increases in the availability of donors.

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Articles in this issue

DOI: https://doi.org/10.14797/mdcvj.1579 | Journal eISSN: 1947-6108

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Language: English

Page range: 5 - 12

Submitted on: Feb 4, 2025

Accepted on: Apr 1, 2025

Published on: May 15, 2025

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

heart transplant,

history of heart transplant,

cardiac transplant,

transplantation

© 2025 Farhan Ishaq, Ashrith Guha, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 21 (2025): Issue 3