References
- Jou S, Mendez SR, Feinman J, et al. Heart transplantation: advances in expanding the donor pool and xenotransplantation. Nat Rev Cardiol. 2024 Jan;21(1):25-36. doi: 10.1038/s41569-023-00902-1
- Singh TP, Cherikh WS, Hsich E, et al. Graft survival in primary thoracic organ transplant recipients: A special report from the International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2023 Oct;42(10):1321-1333. doi: 10.1016/j.healun.2023.07.017
- Colvin MM, Smith JM, Ahn YS, et al. OPTN/SRTR 2022 Annual Data Report: Heart. Am J Transplant. 2024 Feb;24(2S1):S305-S393. doi: 10.1016/j.ajt.2024.01.016
- OPTN [Internet]. Richmond, VA: Organ Procurement & Transplantatin Network; c2025.
National data ; 2025 [cited 2025 Jan 27]. Available from:https://optn.transplant.hrsa.gov/data/view-data-reports/national-data/# - Powell D, Alpert A, Pacula RL. A Transitioning Epidemic: How The Opioid Crisis Is Driving The Rise In Hepatitis C. Health Aff (Millwood). 2019 Feb;38(2):287-294. doi: 10.1377/hlthaff.2018.05232
- Schlendorf KH, Zalawadiya S, Shah AS, et al. Early outcomes using hepatitis C-positive donors for cardiac transplantation in the era of effective direct-acting anti-viral therapies. J Heart Lung Transplant. 2018 Jun;37(6):763-769. doi: 10.1016/j.healun.2018.01.1293
- Schlendorf KH, Zalawadiya S, Shah AS, et al. Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C. JAMA Cardiol. 2020 Feb 1;5(2):167-174. doi: 10.1001/jamacardio.2019.4748
- Villegas-Galaviz J, Anderson E, Guglin M. Clinical outcomes of heart transplantation using hepatitis c-viremic donors: A systematic review with meta-analysis. J Heart Lung Transplant. 2022 Apr;41(4):538-549. doi: 10.1016/j.healun.2022.01.010
- Morris K, James A, Beaudrie N, Patel A. Increased rates of rejection in discordant hepatitis C heart transplantation. J Heart Lung Transplant. 2021;40(4):S75. doi: 10.1016/j.healun.2021.01.1924
- Gidea CG, Narula N, Reyentovich A, et al. Increased early acute cellular rejection events in hepatitis C-positive heart transplantation. J Heart Lung Transplant. 2020 Nov;39(11):1199-1207. doi: 10.1016/j.healun.2020.06.022
- Kadosh BS, Birs AS, Flattery E, et al. Cardiac allograft vasculopathy in heart transplant recipients from hepatitis C viremic donors. Clin Transplant. 2024 Apr;38(4):
e15294 . doi: 10.1111/ctr.15294 - Amancherla K, Feurer ID, Rega SA, et al. Early Assessment of Cardiac Allograft Vasculopathy Risk Among Recipients of Hepatitis C Virus-infected Donors in the Current Era. J Card Fail. 2024 May;30(5):694-700. doi: 10.1016/j.cardfail.2023.09.015
- Aslam S, Grossi P, Schlendorf KH, et al. Utilization of hepatitis C virus-infected organ donors in cardiothoracic transplantation: An ISHLT expert consensus statement. J Heart Lung Transplant. 2020 May;39(5):418-432. doi: 10.1016/j.healun.2020.03.004
- Iyer A, Gao L, Doyle A, et al. Increasing the tolerance of DCD hearts to warm ischemia by pharmacological postconditioning. Am J Transplant. 2014 Aug;14(8):1744-52. doi: 10.1111/ajt.12782
- Dhital KK, Iyer A, Connellan M, et al. Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series. Lancet. 2015 Jun 27;385(9987):2585-91. doi: 10.1016/S0140-6736(15)60038-1
- Dhital K, Ludhani P, Scheuer S, Connellan M, Macdonald P. DCD donations and outcomes of heart transplantation: the Australian experience. Indian J Thorac Cardiovasc Surg. 2020 Aug;36(Suppl 2):224-232. doi: 10.1007/s12055-020-00998-x
- Schroder JN, Patel CB, Devore AD, et al. Transplantation outcomes with donor hearts after circulatory death. N Engl J Med. 2023 Jun 8;388(23):2121-2131. doi: 10.1056/NEJMoa2212438
- Siddiqi HK, Trahanas J, Xu M, et al. Outcomes of Heart Transplant Donation After Circulatory Death. J Am Coll Cardiol. 2023 Oct 10;82(15):1512-1520. doi: 10.1016/j.jacc.2023.08.006
- Zong J, Ye W, Yu J, et al. Outcomes of Heart Transplantation From Donation After Circulatory Death: An Up-to-date Systematic Meta-analysis. Transplantation. 2024 Sep 1;108(9):e264-e275. doi: 10.1097/TP.0000000000005017
- Benkert AR, Keenan JE, Schroder JN, et al. Early U.S. Heart Transplant Experience With Normothermic Regional Perfusion Following Donation After Circulatory Death. JACC Heart Fail. 2024 Dec;12(12):2073-2083. doi: 10.1016/j.jchf.2024.06.007
- Schroder JN, Patel CB, DeVore AD, et al. Increasing Utilization of Extended Criteria Donor Hearts for Transplantation: The OCS Heart EXPAND Trial. JACC Heart Fail. 2024 Mar;12(3):438-447. doi: 10.1016/j.jchf.2023.11.015
- D’Alessandro D, Schroder J, Meyer DM, et al. Impact of controlled hypothermic preservation on outcomes following heart transplantation. J Heart Lung Transplant. 2024 Jul;43(7):1153-1161. doi: 10.1016/j.healun.2024.03.010
- McGiffin DC, Kure CE, Macdonald PS, et al. Hypothermic oxygenated perfusion (HOPE) safely and effectively extends acceptable donor heart preservation times: Results of the Australian and New Zealand trial. J Heart Lung Transplant. 2024 Mar;43(3):485-495. doi: 10.1016/j.healun.2023.10.020
- Jawitz OK, Raman V, DeVore AD, et al. Increasing the United States heart transplant donor pool with donation after circulatory death. J Thorac Cardiovasc Surg. 2020 May;159(5):e307-e309. doi: 10.1016/j.jtcvs.2019.09.080
- Chan A. US Organ Donation Policy. JAMA. 2020 Jan 21;323(3):278-279. doi: 10.1001/jama.2019.18637
- Arshad A, Anderson B, Sharif A. Comparison of organ donation and transplantation rates between opt-out and opt-in systems. Kidney Int. 2019 Jun;95(6):1453-1460. doi: 10.1016/j.kint.2019.01.036
- Cronin AJ. Points mean prizes: priority points, preferential status and directed organ donation in Israel. Isr J Health Policy Res. 2014 Feb 24;3(1):8. doi: 10.1186/2045-4015-3-8
- Johnson EJ, Goldstein D. Medicine. Do defaults save lives? Science. 2003 Nov 21;302(5649):1338-9. doi: 10.1126/science.1091721
- Quigley M, Brazier M, Chadwick R, Michel MN, Paredes D. The organs crisis and the Spanish model: theoretical versus pragmatic considerations. J Med Ethics. 2008 Apr;34(4):223-4. doi: 10.1136/jme.2007.023127
- Dallacker M, Appelius L, Brandmaier AM, Morais AS, Hertwig R. Opt-out defaults do not increase organ donation rates. Public Health. 2024 Nov:236:436-440. doi: 10.1016/j.puhe.2024.08.009
- Glazier A, Mone T. Success of Opt-In Organ Donation Policy in the United States. JAMA. 2019 Aug 27;322(8):719-720. doi: 10.1001/jama.2019.9187
- Siminoff LA, Agyemang AA, Traino HM. Consent to organ donation: a review. Prog Transplant. 2013 Mar;23(1):99-104. doi: 10.7182/pit2013801
- Wall AE, Adams BL, Brubaker A, et al. The American Society of Transplant Surgeons Consensus Statement on Normothermic Regional Perfusion. Transplantation. 2024 Feb 1;108(2):312-318. doi: 10.1097/TP.0000000000004894
- Michetti CP, Newcomb A, Thota V, Liu C. Organ donation education in the ICU setting: a qualitative and quantitative analysis of family preferences. J Crit Care. 2018 Dec:48:135-139. doi: 10.1016/j.jcrc.2018.08.032
- Doerry K, Oh J, Vincent D, Fischer L, Schulz-Jürgensen S. Religious and cultural aspects of organ donation: Narrowing the gap through understanding different religious beliefs. Pediatr Transplant. 2022 Nov;26(7):
e14339 . doi: 10.1111/petr.14339 - Goldman JD, Pouch SM, Woolley AE, et al. Transplant of organs from donors with positive SARS-CoV-2 nucleic acid testing: A report from the organ procurement and transplantation network ad hoc disease transmission advisory committee. Transpl Infect Dis. 2023 Feb;25(1):
e14013 . doi: 10.1111/tid.14013 - Madan S, Chan MAG, Saeed O, et al. Early Outcomes of Adult Heart Transplantation From COVID-19 Infected Donors. J Am Coll Cardiol. 2023 Jun 20;81(24):2344-2357. doi: 10.1016/j.jacc.2023.04.022
- Moazami N, Stern JM, Khalil K, et al. Pig-to-human heart xenotransplantation in two recently deceased human recipients. Nat Med. 2023 Aug;29(8):1989-1997. doi: 10.1038/s41591-023-02471-9
- Taylor DA, Parikh RB, Sampaio LC. Bioengineering Hearts: Simple yet Complex. Curr Stem Cell Rep. 2017;3(1):35-44. doi: 10.1007/s40778-017-0075-7
- Krebs CE, McCarthy J, Sullivan K, Craner J, Parent B, Lam A. Considering the Risks and Costs of Solid Organ Xenotransplantation. Adv Biol (Weinh). 2025 Feb 13:
e2400453 . doi: 10.1002/adbi.202400453
DOI: https://doi.org/10.14797/mdcvj.1577 | Journal eISSN: 1947-6108
Language: English
Page range: 33 - 39
Submitted on: Jan 31, 2025
Accepted on: Mar 6, 2025
Published on: May 15, 2025
Published by: Houston Methodist DeBakey Heart & Vascular Center
In partnership with: Paradigm Publishing Services
Keywords:
© 2025 Saleem Toro, Kelly H. Schlendorf, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.