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Myocardial Recovery in Cardiogenic Shock Cover

Myocardial Recovery in Cardiogenic Shock

Methodist DeBakey Cardiovascular Journal
Volume 20 (2024): Issue 4
By: ,  ,   and    
Open Access
|Aug 2024
Figures & tables

Figures & Tables

Table 1

Predictors of recovery and outcomes in cardiogenic shock. EKG: electrocardiography; HF-CS: heart failure cardiogenic shock; MI-CS: myocardial infarction cardiogenic shock; LVEF: left ventricular ejection fraction; PAPi: pulmonary artery pulsatility index; (+) predictor of better outcome, (-) predictor of worse outcome

HF-CSMI-CS
Imaging/EKG

  • Absence of left bundle branch block (+)

  • LVEF80

  • End-systolic and end-diastolic volumes (+)

  • Improvement in valvular regurgitation (+)

  • Presence of viable myocardial segments (+)

  • LVEF80

  • Chronic total occlusion in non-infarct related artery 14

  • Infarct related artery supplying large area13

Hemodynamics

  • PAPi – predictor of RV failure

  • Baseline SBP(1)

  • Cardiac power output (CPO) - strongest independent parameter of in-hospital mortality81

  • PAPi – predictor of RV failure

  • Shock index (HR/SBP)82

Biomarkers

  • Lactate28

  • NT-proBNP, BNP20

  • IL-619

  • Soluble ST221

  • Dipeptidyl peptidase 323

  • Adrenomedullin22

  • Lactate28

  • Cardiac troponins24

  • Solube ST221

  • Dipeptidyl peptidase 323

  • Adrenomedullin22

  • Angiopoietin-283

  • Cardiogenic Shock 4 Proteins (CS4P) complex- liver fatty acid-binding protein (L-FABP), beta-2-micro- globulin (B2M), fructose-bisphosphate aldolase B (ALDOB), and SerpinG1 (IC1)24

Miscellaneous

  • Female sex (+)

  • Non-ischemic etiology (+)

  • Younger age (+)

Figure 1

Approaches to promote myocardial recovery after cardiogenic shock. MCS: myocardial cardiogenic shock; IABP: intra-aortic balloon pump; LVAD: left ventricular assist device; TAVR: transcatheter aortic valve replacement; TEER: transcatheter edge-to-edge repair; SSO2: super-saturated oxygen; ECMO: extracorporeal membrane oxygenation; VT: ventricular tachycardia; GDMT: guideline-directed medical therapy

DOI: https://doi.org/10.14797/mdcvj.1383 | Journal eISSN: 1947-6108
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Language: English
Page range: 64 - 75
Submitted on: Mar 30, 2024
Accepted on: Jun 25, 2024
Published on: Aug 20, 2024
Published by: Houston Methodist DeBakey Heart & Vascular Center
In partnership with: Paradigm Publishing Services
Keywords:
cardiogenic shock,
myocardial recovery,
mechanical circulatory support,
guideline-directed medical therapy

© 2024 Kevin John, Adnan Khalif, Masaki Tsukashita, Manreet K. Kanwar, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 20 (2024): Issue 4
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