Feasibility of Mediastinal Radiation Use in HeartMate 3 LVAD Recipients with Cancer

Nausharwan Butt; Farooq H. Sheikh

doi:10.14797/mdcvj.1115

Feasibility of Mediastinal Radiation Use in HeartMate 3 LVAD Recipients with Cancer

Methodist DeBakey Cardiovascular Journal

Volume 19 (2023): Issue 1

By: Nausharwan Butt and Farooq H. Sheikh

Open Access

|Jan 2023

Abstract

The HeartMate 3 left ventricular assist device possesses the unique feature of having its electronics and software located within the housing of the pump, which may predispose it to malfunction from radiation exposure during cancer treatment. We investigated this association in a case series of two patients at our institution.

References

Farrar DJ, Bourque K, Dague CP, Cotter CJ, Poirier VL. Design features, developmental status, and experimental results with the Heartmate III centrifugal left ventricular assist system with a magnetically levitated rotor. ASAIO J. 2007 May-Jun;53(3):310-5. doi: 10.1097/MAT.0b013e3180536694
Open DOI Search in Google Scholar Back to article
Chelikani NM, Masterson K, Down LA, et al. Effects of gamma radiation on a ventricular assist device and its percutaneous lead components. Asaio J. 2012 Jan-Feb;58(1):19-24. doi: 10.1097/MAT.0b013e31823e5bcc
Open DOI Search in Google Scholar Back to article
Gossman MS, Graham JD, Das IJ, et al. Evaluation of a ventricular assist device system: stability in a proton beam therapy. Asaio J. 2012 Nov-Dec;58(6):597-600. doi: 10.1097/MAT.0b013e31826feeca
Open DOI Search in Google Scholar Back to article
Gossman MS, Graham JD, Tamez D, Voskoboynikov N, Larose JA. Evaluation of a ventricular assist device: stability under x-rays and therapeutic beam attenuation. Asaio J. 2012 May-Jun;58(3):212-6. doi: 10.1097/MAT.0b013e3182468318
Open DOI Search in Google Scholar Back to article
Makkar A, Prisciandaro J, Agarwal S, et al. Effect of radiation therapy on permanent pacemaker and implantable cardioverter-defibrillator function. Heart Rhythm. 2012 Dec;9(12):1964-8. doi: 10.1016/j.hrthm.2012.08.018
Open DOI Search in Google Scholar Back to article
Brouillard É, Chamula M, Lavoie C, Varfalvy N, Archambault L. Radiation Therapy-Induced Dysfunction in Cardiovascular Implantable Electronic Devices. Pract Radiat Oncol. 2019 Jul-Aug;9(4):266-273. doi: 10.1016/j.prro.2019.03.003
Open DOI Search in Google Scholar Back to article
Abbott [Internet]. Abbott Park, IL: Abbot Laboratories; c2022. HeartMate 3 Instructions for Use; 2022 [cited 2022 Nov 29]. Available from: https://www.cardiovascular.abbott/us/en/hcp/products/heart-failure/left-ventricular-assist-devices/heartmate-3/manuals-resources.html
Search in Google Scholar Back to article
Spano G, Stutz E, Elicin O, et al. Is it safe to irradiate the newest generation of ventricular assist devices? A case report and systematic literature review. Artif Organs. 2020 May;44(5):449-456. doi: 10.1111/aor.13612
Open DOI Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.14797/mdcvj.1115 | Journal eISSN: 1947-6108

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Language: English

Page range: 15 - 19

Submitted on: Apr 4, 2022

Accepted on: Nov 23, 2022

Published on: Jan 23, 2023

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

HeartMate LVAD,

mediastinal cancer,

radiation exposure,

stereotactic bone radiation therapy

© 2023 Nausharwan Butt, Farooq H. Sheikh, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 19 (2023): Issue 1