BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition

Abdul Wahab Arif; Muhammad Shahzeb Khan; Abdallah Masri; Benjamin Mba; Muhammad Talha Ayub; Rami Doukky

doi:10.14797/mdcj-16-3-241

BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition

Methodist DeBakey Cardiovascular Journal

Volume 16 (2020): Issue 3

By: Abdul Wahab Arif, Muhammad Shahzeb Khan, Abdallah Masri, Benjamin Mba, Muhammad Talha Ayub and Rami Doukky

Open Access

|Jul 2020

Abstract

BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient with a low glomerular filtration rate taking an AVNB. Decreased clearance of the medication and hyperkalemia associated with renal failure synergize to cause bradycardia and hypoperfusion. This reaction causes renal function to worsen, thereby perpetuating the cycle of BRASH syndrome.

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Articles in this issue

DOI: https://doi.org/10.14797/mdcj-16-3-241 | Journal eISSN: 1947-6108

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Language: English

Page range: 241 - 244

Published on: Jul 1, 2020

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

bradycardia,

renal failure,

atrioventricular nodal blocker,

shock,

hyperkalemia,

BRASH syndrome

© 2020 Abdul Wahab Arif, Muhammad Shahzeb Khan, Abdallah Masri, Benjamin Mba, Muhammad Talha Ayub, Rami Doukky, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 16 (2020): Issue 3