Figure 1.
The three oxidative states of CoQ10: the fully reduced ubiquinol form (CoQ10H2), the radical semiquinone intermediate (CoQ10H.), and the fully oxidized ubiquinone form (CoQ10).
Figure 2.
Forest plot for statin-associated muscle symptoms: Coenzyme Q10 versus placebo. CI: confidence interval; ID: study identification; WMD: weighted mean difference. Reprinted with permission.15
Figure 3.
Kaplan-Meyer estimates of (A) the time to primary end point (major adverse cardiac events, or MACE), and (B) secondary end point (death) in the Q-SYMBIO trial. MACE included cardiovascular death, mechanical support, hospital stay for worsening heart failure, and urgent cardiac transplantation. A specified secondary outcome was death from any cause. Reprinted with permission.22