Cardiovascular Disease in Acromegaly

Morali D. Sharma; Anh V. Nguyen; Spandana Brown; Richard J. Robbins

doi:10.14797/mdcj-13-2-64

Cardiovascular Disease in Acromegaly

Methodist DeBakey Cardiovascular Journal

Volume 13 (2017): Issue 2

By: Morali D. Sharma, Anh V. Nguyen, Spandana Brown and Richard J. Robbins

Open Access

|Apr 2017

Abstract

In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

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Articles in this issue

DOI: https://doi.org/10.14797/mdcj-13-2-64 | Journal eISSN: 1947-6108

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Language: English

Page range: 64 - 67

Published on: Apr 1, 2017

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

coronary artery disease,

arrhythmia,

valvular heart disease

© 2017 Morali D. Sharma, Anh V. Nguyen, Spandana Brown, Richard J. Robbins, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 13 (2017): Issue 2