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Novel Nanoprinting for Oral Delivery of Poorly Soluble Drugs Cover

Novel Nanoprinting for Oral Delivery of Poorly Soluble Drugs

Open Access
|Jul 2016

Figures & Tables

Figure 1.

Fabrication of 3D nanorods (NRs) fabricated by fast and scalable directed assembly method. (a) Schematic of fabrication process. (b) Billions of NRs fabricated on a substrate. (c) 30-nm diameter NR fabricated from PEG-PE micelles. (d) 100-nm diameter NR fabricated from paclitaxel drug-loaded PEG-PE. PEG-PE: polyethylene glycol-phosphatidylethanolamine

Figure 2.

(a) Preparation of a paclitaxel drug-loaded tagged micellar system. (b) Fabrication and harvesting of orally acceptable 3-dimensional drug-loaded micellar nanorods (NRs) using electric field directed assembly. Red and black colors of the NRs indicate the dye and the drug incorporated into micelles, respectively. (c) Optical and scanning electron microscopy images of the drug-loaded micelles embedded in a water-soluble polymer before and after harvested from the substrate.

Figure 3.

Product concept from the production of the drug-loaded nanorods to delivery to the tumor cells.

Language: English
Page range: 157 - 162
Published on: Jul 1, 2016
Published by: Houston Methodist DeBakey Heart & Vascular Center
In partnership with: Paradigm Publishing Services

© 2016 Cihan Yilmaz, Can Sarisozen, Vladimir Torchilin, Ahmed Busnaina, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.