Figure 1
Schematic representation of Gα12/Gα13-containing signaling complexes assembled by A-kinase anchoring proteins (AKAPs): AKAP-Lbc (A) and AKAP-110 (B). See main text for details and references.
Figure 2
Signaling complexes assembled by TPR-repeat scaffolding proteins: TPR1 (A) and RACK1 (B). See main text for description.
Figure 3
Signaling from the Gα13-radixin complex.
Figure 4
The role of EBP50 (NERF) in downregulation of G protein signaling.
Figure 5
Scaffolding proteins that link subunits of heterotrimeric G proteins with MAP kinase cascade. A, The role of Ste5 in the mating signaling in yeast. B, Signaling complex assembled by KSR1, leading to ERK activation. C, Signaling complex assembled by JLP, leading to activation of JNK (or p38, see discussion in the main text). LPA, lysophosphatidic acid; RA, retinoic acid.