Table 1
Comparison of some variables between Restless Legs Syndrome (RLS) patients and control subjects
| Variable | RLS (n = 98) | Control (n = 670) | P | Total (n = 768) |
| Age (year) | ||||
| Mean (SD) | 35.2 (5.9) | 32.7 (5.8) | <0.001 | 33 (5.9) |
| Range | 24-50 | 20-58 | 20-58 | |
| Work experience (year) | ||||
| Mean (SD) | 11.8 (5.3) | 8.9 (4.7) | <0.001 | 9.3 (4.9) |
| Range | 2-25 | 0.5-27 | 0.5-27 | |
| Current smokers, n (%) | 19 (19.4) | 87 (12.9) | 0.115 | 106 (13.8) |
| Chronic disorders, n (%) | ||||
| Anemia | 6 (6.1) | 24 (3.6) | 0.258 | 30 (3.9) |
| Diabetes mellitus | 4 (4.1) | 18 (2.7) | 0.51 | 22 (2.9) |
| Chronic kidney disease | 1 (1) | 2 (0.3) | 0.336 | 3 (0.4) |
| Total | 11 (11.2) | 44 (6.6) | 0.097 | 55 (7.2) |
| Drug consumption, n (%) | ||||
| Antihistamines | 16 (16.3) | 29 (4.32) | <0.001 | 45 (5.85) |
| Antidepressants | 6 (6.1) | 23 (3.43) | 0.248 | 29 (3.77) |
| Dopamine antagonist | 2 (2) | 15 (2.23) | 1.0 | 17 (2.21) |
| Total | 24 (24.4) | 67 (10) | <0.001 | 91 (11.8) |
Table 2
Relation of shift work patterns with occurrence of Restless Legs Syndrome (RLS)
| Group | Suffering from RLS | Crude OR [95% CI] | Adjusted* OR [95% CI] | |
| No | Yes | |||
| Day workers (Group A), n (%) | 238 (91.5) | 22 (8.5) | 1.0 Reference | 1.0 Reference |
| Rotational shift workers, n (%) | ||||
| - Group B | 220 (85.3) | 38 (14.7) | 1.87 [1.07-3.26]§ | 1.82 [1.03-3.21]§ |
| - Group C | 212 (84.8) | 38 (15.2) | 1.94 [1.11-3.38]§ | 1.98 [1.12-3.51]§ |
| - Groups B and C | 432 (85) | 76 (15) | 1.9 [1.15-3.14]§ | 1.89 [1.13-3.16]§ |
Notes: Group B: workers who follow a work schedule which consists of weekly rotation between morning and afternoon shifts for five weeks in a row, followed by one week of night shifts on week six; Group C: workers who follow a work schedule which consists of weekly rotation between morning, afternoon and night shifts; n = number; OR = odds ratio; CI = confidence interval
* This analysis was adjusted by age and drug consumption.
§ P-value < 0.05
Table 3
Comparison of Restless Legs Syndrome severity and weekly occurrence between groups
| Group | Severity Scale | Weekly occurrence | ||
| < 21 | ≥ 21 | < 4 day | ≥ 4 day | |
| Day workers (Group A), n (%) | 11 (50) | 11 (50) | 13 (59.1) | 9 (40.9) |
| Rotational shift workers, n (%) | ||||
| - Group B | 14 (36.8) | 24 (63.2) | 16 (42.1) | 22 (57.9) |
| - Group C | 11 (28.9) | 27 (71.1) | 18 (47.4) | 20 (52.6) |
| - Groups B and C | 25 (32.9) | 51 (67.1) | 34 (44.7) | 42 (55.3) |
Notes: Group B: workers who follow a work schedule which consists of weekly rotation between morning and afternoon shifts for five weeks in a row, followed by one week of night shifts on week six; Group C: workers who follow a work schedule which consists of weekly rotation between morning, afternoon and night shifts.