Table 1
Demographic and subjective sleep data of subjects (N = 86)
| Mean (SD) or percentage (n) | |
| Sex | 80.2% female (69) |
| Age | 30.05 (5.2) |
| Mean BMI in kg/m2 | 26.7 (3.1) |
| Subjective sleep onset latency in min | 37.5 (41.3) |
| Subjective number of awakenings | 5.2 (2.1) |
| Subjective duration of sleep in min | 450.5 (82.3) |
Table 2
Subjective sleep parameters during a randomized, double-blind, placebo-controlled crossover study of shift work nurses: results at baseline and after 1 night melatonin or placebo treatment (N = 86)
| Mean | SD | P(vs.baselinea) | P(vs.placeboa) | Fb | Pb | ||
| Sleep onset latency | Melatonin | 21.5 | 17.7 | < 0.05 | < 0.05 | 6.3 | 0.01 |
| Placebo | 49.7 | 30.3 | < 0.05 | ||||
| Baseline | 37.5 | 41.3 | |||||
| Total sleep time | Melatonin | 392.1 | 52.4 | > 0.05 | > 0.05 | 0.49 | NS |
| Placebo | 372 | 49.4 | > 0.05 | ||||
| Baseline | 450.5 | 82.3 | |||||
| Number of awakenings | Melatonin | 5.1 | 1.9 | > 0.05 | > 0.05 | 0.64 | NS |
| Placebo | 5.1 | 1.9 | > 0.05 | ||||
| Baseline | 5.2 | 2.1 |
a p values for Tukey post hoc analysis.
b Overall test for differences
Table 3
Subjective assessment of insomnia: results at baseline and after 1 night of melatonin or placebo treatment (N = 86)
| Mean | SD | P(vs.baselinea) | P(vs.placeboa) | Fb | Pb | ||
| Difficulty falling asleep | Melatonin | 1.63 | 0.61 | < 0.05 | < 0.05 | 4.5 | 0.01 |
| Placebo | 2.53 | 0.62 | > 0.05 | ||||
| Baseline | 2.67 | 0.80 | |||||
| Difficulty staying asleep | Melatonin | 2.32 | 0.83 | > 0.05 | > 0.05 | 0.71 | NS |
| Placebo | 2.31 | 0.69 | > 0.05 | ||||
| Baseline | 2.48 | 1.11 | |||||
| Problem waking up too early | Melatonin | 2.26 | 0.81 | > 0.05 | > 0.05 | 0.42 | NS |
| Placebo | 2.40 | 0.74 | > 0.05 | ||||
| Baseline | 2.39 | 1.29 | |||||
| Sleep quality | Melatonin | 2.58 | 0.76 | < 0.05 | < 0.05 | 1.2 | 0.02 |
| Placebo | 2.69 | 0.67 | > 0.05 | ||||
| Baseline | 3.16 | 0.92 |
a p values for Tukey post hoc analysis.
b Overall test for differences