Table 1
Setup of experimental rat groups
| Adriamycin (8 mg/kg i.v.) | ||
| Laparotomy Day | 9 a.m | 9 p.m |
| 0 | Group 1 | Group 2 |
| 7 | Group 3 | Group 4 |
| 14 | Group 5 | Group 6 |
| 21 | Group 7 | Group 8 |
Sample size for each groups n = 15.
Table 2
Temporal variation induced by adriamycin (8 mg/kg, i.v.) administration on blast pressure after laparotomy
| Blast pressures (mmHg) | ||
| Laparotomy Day | Injection times of adriamycin | |
| 9 a.m | 9 p.m | |
| 0 | 112.5 ± 12.2* | 101.8 ± 5.6 |
| 7 | 97.1 ± 4.2* | 86.3 ± 6.3 |
| 14 | 79.1 ± 8.0* | 65.1 ± 5.3 |
| 21 | 83.1 ± 3.7* | 72.0 ± 3.1 |
Data represents the means ± S.E.M; Sample size for each group: n = 15.
* 9 a.m. vs 9 p.m. on same laparatomy days p ≤ 0.05
Table 3
Temporal variations induced by adriamycin (8 mg/kg, i.v.) administration on hydroxyproline levels after laparotomy
| Hydroxyproline (μg/mg wet tissue) | ||
| Laparotomy Day | Injection times of adriamycin | |
| 9 a.m | 9 p.m | |
| 0 | 7.0 ± 1.1 | 6.8 ± 0.9 |
| 7 | 5.7 ± 0.2 | 5.6 ± 0.2 |
| 14 | 5.9 ± 0.9 | 5.8 ± 0.9 |
| 21 | 5.7 ± 0.3 | 5.7 ± 0.4 |
Shown are means ± S.E.M. Sample size for each group n = 15. * 9 a.m. vs 9 p.m. on same laparatomy days p ≤ 0.05