Figure 1
24-hour Cosine Curve fit to Mean Core Body Temperature (°F). Time course of CBT according to time of day. Shown is a double plot of the group (n = 11) mean levels (+/- SEM) of CBT (blue diamonds) fit with a 24-hour cosine curve (purple squares). Time of day is shown on the abscissa. The ordinate shows CBT values (degrees F). The vertical line indicates where the data was double plotted. Also displayed in the upper right corner is the non-linear cosine curve fit for mean CBT, R2 = 0.62. The overall mean circadian phase position of the minimum was 6:05 am.
Figure 2
24-hour Cosine Curve fit to Mean Cerebral Blood Flow Velocity (cm/sec). Time course of CBFV according to time of day. Shown is a double plot of the group (n = 11) mean levels (+/- SEM) of CBFV (blue diamonds) fit with a 24-hour cosine curve (purple squares). Time of day is shown on the abscissa. The ordinate shows CBFV values (cm/sec). The vertical line indicates where the data was double plotted. Also displayed in the upper right corner is the non-linear cosine curve fit for mean CBFV, R2 = 0.67. The overall mean circadian phase position of the minimum was 12:02 pm.
Figure 3
Mean CBT and CBFV Aligned to CBT Nadir. Time course of mean CBFV and mean CBT aligned to the nadir of CBT and then averaged. Shown is a double plot of the group (n = 11) mean levels (+/-SEM) of CBT (purple squares) and CBFV (blue circles) aligned to the phase of the circadian temperature cycle. Circadian time in degrees is shown on the abscissa. The ordinate on the left shows CBT values (degrees F) and CBFV (cm/sec) on the right. The vertical line indicates the CBT nadir.
Figure 4
Mean CBT and CBFV Aligned to Their Respective Nadir. Time course of mean CBFV and mean CBT aligned to each of their respective nadirs and then averaged. Shown is a double plot of the group (n = 11) mean levels (+/-SEM) of CBT (purple squares) and CBFV (blue circles) aligned to the phase of the circadian temperature cycle. Circadian time in degrees is shown on the abscissa. The ordinate on the left shows CBT values (degrees F) and CBFV (cm/sec) on the right. The vertical line indicates both the CBT nadir and the CBFV nadir. The correlation coefficient between the aligned rhythms is 0.77 (p < 0.01).