Table 1
Content of the CE and EBM module
|
Topic |
Methods |
Modulea |
|---|---|---|
|
Introduction to evidence-based medicine |
Lecture |
EBM |
|
How to make an evidence-based case report |
Lecture |
EBM |
|
Making an answerable clinical question |
Lecture |
EBM |
|
Frequency and association measures |
Lecture |
CE |
|
Diagnosis |
Lecture |
CE |
|
Prognosis |
Lecture |
CE |
|
Formulation of the clinical question; search and comparison of study-book knowledge, study of EBCR design |
Group work |
EBM |
|
Intervention |
Lecture |
CE |
|
Aetiology |
Lecture |
CE |
|
Critical appraisals |
Lecture |
EBM |
|
Internet literature search |
Practical lecture |
EBM |
|
Computer exercise on prognosis and diagnosis |
Practical lecture |
CE |
|
Exercise critical appraisal on therapy |
Group work |
EBM |
|
Establishing the search query, literature search and selection, critical appraisal of the selected papers regarding their relevance and methods, description of methods and (provisional) results |
Group work |
EBM |
|
Levels of evidence |
Lecture |
EBM |
|
Computer exercise on aetiology and intervention |
Practical lecture |
CE |
|
Exercise critical appraisal on prognosis and diagnosis |
Group work |
EBM |
|
Sorting and structurally summarize the search and appraisal; description of methods and (provisional) results |
Group work |
EBM |
|
Exercise critical appraisal on aetiology |
Group work |
EBM |
|
Report of EBCR both orally and in writing according to the requirements for form, structure and content; formulation of a recommendation for patient care and further research |
Group work |
EBM |
aBased on the original structure in UMCU where the CE and EBM were given in separate module
Table 2
Comparison of the CE-EBM module structure in UI, UM and UMCU
|
Educational activities within the module |
Time allocation (h) | |||
|---|---|---|---|---|
|
UI |
UM |
UMCU | ||
|
CE |
EBM | |||
|
Lectures |
30 |
22 |
20 |
20 |
|
Computer practical |
6 |
8 |
10 |
3 |
|
Tutorial working group |
18 |
14 |
5 |
8 |
|
Collaborative and individual learninga |
45 |
0 |
110 |
55 |
|
Plenary presentation |
4 × 3 |
2 × 3 |
4 × 3 |
4 × 3 |
|
Total hours |
111 |
50 |
157 |
98 |
|
Module duration |
4 week |
3 months |
6 weeks |
5 weeks |
aSpecifically allocated within the module as listed in the schedule
Table 3
Comparison of pre- and post-knowledge test results and evidence-based case report (EBCR) score between UI, UM and UMCU
|
UMCU |
UI |
UM | |
|---|---|---|---|
|
Pre-test scores | |||
|
N |
389 |
196 |
160 |
|
Mean (SD) |
62.20 (9.21) |
54.69 (10.51) |
46.23 (8.69) |
|
Minimum |
9.38 |
31.58 |
28.12 |
|
Maximum |
87.50 |
92.11 |
68.75 |
|
Mean difference (95 % CI) |
7.52 (5.85–9.18) |
15.97 (14.30–17.64) | |
|
p value |
<0.001* |
<0.001* | |
|
Post-test scores | |||
|
N |
377 |
196 |
200 |
|
Mean (SD) |
74.75 (9.66) |
73.54 (10.13) |
61.39 (10.39) |
|
Minimum |
31.25 |
34.21 |
18.75 |
|
Maximum |
100 |
89.48 |
81.25 |
|
Mean difference (95 % CI) |
1.32 (0.40–3.04) |
13.36 (11.66–15.06) | |
|
p value |
0.484† |
<0.001† | |
|
Difference in scores | |||
|
N |
350 |
196 |
159 |
|
Post-test minus pre-test |
12.54 (11.44) |
18.85 (12.81) |
17.51 (9.49) |
|
Mean difference (95 % CI) |
6.32 (4.22–8.41) |
4.98 (2.93–7.02) | |
|
p value |
<0.001* |
<0.001* | |
|
EBCR | |||
|
N |
71 |
40 |
40 |
|
Median |
8.0 |
8.4 |
7.8 |
|
Minimum |
5 |
7.5 |
7 |
|
Maximum |
10 |
9.0 |
8.6 |
|
p value |
0.001‡ |
0.44‡ | |
* Independent t-test
† Ancova test, which include baseline score as covariate
‡ Mann–Whitney test
Table 4
Examples of clinical questions answered by evidence-based case reports
|
Clinical questions |
Type of question |
|---|---|
|
University of Indonesia | |
|
Is artemether–lumefantrine (AL) as effective as artesunate–amodiaquine (ASAD; standard treatment of malaria therapy in Indonesia) for treating uncomplicated childhood malaria? |
Therapy |
|
Mortality after balloon aortic valvuloplasty in male with severe aortic stenosis |
Prognosis |
|
Is the nitrite test accurate as diagnostic tool in pregnant women? |
Diagnosis |
|
In hospitalised elderly patients, is depression related to higher mortality? |
Prognosis |
|
Could calcium supplementation prevent osteoporotic fracture in post-menopausal women? |
Therapy |
|
Diagnostic value of abdominal radiography to diagnose acute appendicitis in children |
Diagnosis |
|
The effectiveness of normal saline solution vs Ringer’s lactate solution to overcome dengue shock syndrome in children |
Therapy |
|
Is acupuncture effective to decrease pain in patient with chronic back pain? |
Therapy |
|
University of Malaya | |
|
Is exercise stress echocardiography superior in diagnosing patients presenting with chest pain compared with exercise stress electrocardiography? |
Diagnosis |
|
Can Parkinson’s disease be treated more effectively by using dopamine agonists compared with levodopa in Parkinson patients above 50 years? |
Therapy |
|
Do colorectal cancer patients with high levels of tumour markers CEA and CA19-9 have a low 3-year survival rate? |
Prognosis |
|
Does the Revised Trauma Score (RTS) make a good prognostic tool in trauma patients? |
Prognosis |
|
Do children with past history of sexual abuse have increased risk of psychiatric problems in adulthood? |
Prognosis |
|
University Medical Center Utrecht | |
|
The prognostic value of a history of shoulder pain on predicting the duration of pain in patients presenting with a new episode of shoulder pain |
Prognosis |
|
The influence of physiotherapy on pain in patients with shoulder impingement |
Therapy |
|
Diagnostic ultrasound in a patient suspected of a partial rotator cuff rupture |
Diagnosis |
|
Does treatment with heparin in adults diagnosed with cerebral venous thrombosis reduce mortality within 3-months? |
Therapy |
|
CT venography: the new reference test for diagnosing cerebral venous thrombosis? |
Diagnosis |
|
Glasgow Coma Scale as a prognostic factor in sinus thrombosis |
Prognosis |
|
Prognostic value of current smoking for exacerbations in COPD |
Prognosis |
|
For patients with COPD in the primary care setting: what is the predictive value of CRP for community-acquired pneumonia? |
Prognosis |
|
Diagnostic value of BNP for determining chronic heart failure in patients with COPD |
Diagnosis |
