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Genetically Determined Rheumatoid Arthritis May Not Affect Heart Failure: Insights from Mendelian Randomization Study Cover

Genetically Determined Rheumatoid Arthritis May Not Affect Heart Failure: Insights from Mendelian Randomization Study

Open Access
|Aug 2023

Figures & Tables

Table 1

Two-sample Mendelian randomization estimates between rheumatoid arthritis and heart failure.

OUTCOMESNP SELECTIONSNPS,NMETHODOR (95% CI)P-VALUE
HFAll39IVW1.00(0.99–1.02)0.68
MR Egger1.01(0.99–1.03)0.37
Weighted median1.01(0.99–1.02)0.38
Weighted mode1.00(0.99–1.02)0.30
Remove37IVW1.00(0.99–1.01)0.62
MR Egger1.01(0.99–1.03)0.31
Weighted median1.01(0.99–1.02)0.37
Weighted mode1.01(0.99–1.02)0.36

[i] Abbreviation: HF, heart failure; SNPs, single nucleotide polymorphisms; IVW, Inverse Variance Weighted; MR-Egger, Mendelian Randomization-Egger; OR, odd ratios; CI, confidence interval.

DOI: https://doi.org/10.5334/gh.1256 | Journal eISSN: 2211-8179
Language: English
Submitted on: Feb 23, 2023
Accepted on: Jul 19, 2023
Published on: Aug 11, 2023
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Xueqi Lin, Miaomiao Zhou, Chunsheng Zhang, Jiming Li, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.