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Hyperuricemia is Related to the Risk of Cardiovascular Diseases in Ethnic Chinese Elderly Women Cover

Hyperuricemia is Related to the Risk of Cardiovascular Diseases in Ethnic Chinese Elderly Women

Open Access
|Feb 2022

Figures & Tables

Table 1

Baseline characteristics of 6,228 Dong, 4,986 Miao, and 5,404 Bouyei ethnic groups by cardiovascular diseases status.

VARIABLESDONG ETHNIC GROUPMIAO ETHNIC GROUPBOUYEI ETHNIC GROUP
NON-CVDSCVDSPNON-CVDSCVDSPNON-CVDSCVDSP
No. of participants5,978 (96.00)250 (4.00)4,790 (96.07)196 (3.93)5,199 (96.21)205 (3.79)
Age (years)51.96 (44.99–60.13)61.11 (54.12–67.00)<0.00150.45 (42.51–59.18)62.08 (53.68–68.63)<0.00150.87 (43.89–58.05)60.16 (53.11–66.77)<0.001
Men2,052 (34.33)112 (44.80)0.0011,740 (36.33)79 (40.31)0.2571,540 (29.62)85 (41.46)<0.001
Rural4,636 (77.84)188 (75.20)0.3263,421 (71.57)119 (60.71)0.0014,554 (87.59)169 (82.44)0.029
Tobacco smoking status0.1180.5710.736
Never4,761 (79.66)180 (72.00)3,748 (78.25)154 (78.57)4,301 (82.73)164 (80.00)
Former210 (3.51)28 (11.20)171 (3.57)12 (6.12)161 (3.10)21 (10.24)
Current1,006 (16.83)42 (16.80)871 (18.18)30 (15.31)737 (14.18)20 (9.76)
Alcohol drinking weekly188 (3.14)1 (14.00)0.032204 (4.26)9 (4.59)0.821155 (2.98)8 (3.90)0.450
Total physical activity (METs h/d)24.96 (14.00–37.16)17.55 (8.30–30.65)<0.00125.18 (13.40–38.80)12.12 (5.60–27.03)<0.00123.95 (13.37–37.10)14.80 (7.01–28.00)<0.001
Total energy intake (kcal/week)10.22 (8.20–12.97)9.24 (7.35–12.08)<0.00110.61 (8.16–13.67)9.71 (7.84–12.23)0.00110.65 (8.15–13.81)9.94 (7.44–12.83)0.005
BMI (kg/m2)23.74 (21.46–26.15)24.38 (21.81–26.15)0.22424.79 (22.51–27.10)25.50 (22.97–27.80)0.03823.84 (21.59–26.20)24.94 (22.20–27.06)<0.001
SBP (mmHg)121.60 (110.33–135.67)129.50 (115.00–144.00)<0.001122.30 (111.00–136.67)134.30 (118.33–147.67)<0.001121.30 (110.33–135.67)135.30 (120.67–151.33)<0.001
DBP (mmHg)79.00 (72.67–87.00)81.00 (74.67–90.67)0.00380.33 (73.33–88.33)83.33 (75.67–92.00)0.00180.33 (74.00–88.33)86.00 (78.33–94.67)<0.001
FPG (mmol/L)5.29 (4.96–5.68)5.30 (4.94–5.75)0.6435.20 (4.90–5.60)5.45 (5.06–5.92)<0.0015.14 (4.86–5.51)5.28 (5.02–5.73)<0.001
TC (mmol/L)4.87 (4.29–5.51)4.84 (4.10–5.52)0.2674.96 (4.35–5.60)5.04 (4.41–5.98)0.1624.87 (4.31–5.52)4.97 (4.41–5.67)0.081
TG (mmol/L)1.51 (1.08–2.22)1.58 (1.18–2.39)0.1161.43 (1.02–2.12)1.61 (1.22–2.30)0.0021.38 (0.99–2.02)1.57 (1.16–2.14)0.002
HDL-C (mmol/L)1.46 (1.22–1.73)1.37 (1.15–1.62)<0.0011.43 (1.02–2.12)1.43 (1.25–1.60)0.2061.49 (1.32–1.69)1.49 (1.33–1.67)0.772
LDL-C (mmol/L)2.94 (2.38–3.50)2.96 (2.26–3.60)0.8242.81 (2.30–3.40)2.90 (2.35–3.61)0.0422.45 (2.03–2.93)2.54 (2.15–3.13)0.022
SUA (mg/dL)5.36 (4.45–6.52)5.85 (4.87–7.24)<0.0015.39 (4.49–6.45)5.69 (4.86–7.08)<0.0015.02 (4.18–6.08)5.78 (4.60–6.72)<0.001
Scr (µmol/L)65.00 (56.00–77.00)71.00 (59.00–85.00)<0.00162.00 (54.00–74.00)68.00 (59.00–79.50)<0.00160.00 (53.00–70.00)67.00 (57.00–79.00)<0.001
eGFR (mL/min/1.73 m2)81.00 (75.00–87.00)76.00 (70.00–82.00)<0.00184.00 (77.00–90.00)76.00 (71.00–82.00)<0.00184.00 (78.00–90.00)78.00 (72.00–84.00)<0.001
HUA1,545 (25.84)92 (36.80)<0.0011,189 (24.82)66 (33.67)0.005969 (18.64)66 (32.20)<0.001

[i] Abbreviations: BMI, body mass index; CVDs, cardiovascular diseases; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; HUA, hyperuricemia; LDL-C, low-density lipoprotein cholesterol; METs h/d, metabolic equivalent tasks hours/day; SBP, systolic blood pressure; Scr, serum creatinine; SUA, serum uric acid; TC, total cholesterol; TG, triglycerides.

Data are number (percentage) or median (interquartile range).

P comparing non-CVDs and CVDs.

gh-17-1-1102-g1.png
Figure 1

The prevalence of cardiovascular diseases. CHD, coronary heart disease; CVDs, cardiovascular diseases.

gh-17-1-1102-g2.png
Figure 2

The risk of cardiovascular diseases, coronary heart disease, and stroke stratified by sex. Adjusted for age, residence, tobacco smoking status, alcohol drinking status, total physical activity, total energy intake, family history of cardiovascular diseases, body mass index, and systolic blood pressure, fasting plasma glucose, and triglycerides levels. CHD, coronary heart disease; CI, confidence interval; CVDs, cardiovascular diseases; OR, odd ratio.

gh-17-1-1102-g3.png
Figure 3

The risk of cardiovascular diseases, coronary heart disease, and stroke stratified by the median of age. Adjusted for sex, residence, tobacco smoking status, alcohol drinking status, total physical activity, total energy intake, family history of cardiovascular diseases, body mass index, and systolic blood pressure, fasting plasma glucose, and triglycerides levels. CHD, coronary heart disease; CI, confidence interval; CVDs, cardiovascular diseases; OR, odd ratio. The median of age were 52, 51, and 51 years in the Dong, Miao, and Bouyei ethnic groups, respectively.

gh-17-1-1102-g4.png
Figure 4

The risk of cardiovascular diseases, coronary heart disease, and stroke stratified by sex and the median of age. Adjusted for residence, tobacco smoking status, alcohol drinking status, total physical activity, total energy intake, family history of cardiovascular diseases, body mass index, and systolic blood pressure, fasting plasma glucose, and triglycerides levels. CHD, coronary heart disease; CI, confidence interval; CVDs, cardiovascular diseases; NA, not applicable; OR, odd ratio. The median of age were 54, 52, and 52 years in men, 51, 50, and 51 years in women, in the Dong, Miao, and Bouyei ethnic groups, respectively.

DOI: https://doi.org/10.5334/gh.1102 | Journal eISSN: 2211-8179
Language: English
Submitted on: Oct 22, 2021
Accepted on: Jan 20, 2022
Published on: Feb 22, 2022
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2022 Leilei Liu, Xiao Zhang, Lian Peng, Nana Ma, Tingting Yang, Chan Nie, Linyuan Zhang, Zixuan Xu, Jun Yang, Xuejie Tang, Liubo Zheng, Tao Zhang, Feng Hong, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.