The 10-week of aerobic-functional training improves fasting blood sugar, insulin resistance, and lipid profile in patients with diabetic peripheral neuropathy: A randomized controlled trial

Study aim: This study aimed to investigate the effect of a 10-week of combined training course on concentrations of blood sugar, Insulin Resistance (HOMA-IR), and lipid profile in patients with diabetic peripheral neuropathy.

Materials and methods: This clinical trial was performed in diabetic neuropathy women and men (30–60 years old). Participants were randomly assigned to two groups: exercise (EG; n = 10) and control (CG; n = 10). The EG performed 10-week programme with one session of aerobic exercises (40% to 70% of HR_Reserve) and one session of functional exercises (60–90 min/ day) at the same day for four days/week and the CG performed their daily activities. The Blood glucose, IR, and lipid profile were measured initially and after the intervention.

Results: Repeated-measures ANOVA showed significant decrease in fasting blood sugar (p < 0.01) and HOMA-IR (p < 0.01), and greater improvements in TG (p < 0.05) and LDL (p < 0.05) in EG than CG, but. HDL concentration did not show significant changes.

Conclusion: The 10-week of aerobic-functional training improves fasting blood sugar, IR, and lipid profile in patients with diabetic neuropathy.