Antibiotic Resistance Of Bacteria A Growing Threat For Animals And Public Health

Binek, Marian; Kizerwetter-Świda, Magdalena; Rzewuska, Magdalena; Chrobak-Chmiel, Dorota; Sałamaszyńska-Guz, Agnieszka

doi:10.21307/PM-2019.58.3.259

Figures & Tables

Percentage of commensal Escherichia coli strains resistant to selected antimicrobials, isolated from fattening pigs

Country/average in EU	Number of strains tested	Percentage of resistant strains
Country/average in EU	Number of strains tested	Gentamicin	Chloramphenicol	Ampicillin	Cefotaxime	Ceftazidime	Ciprofloxacin	Colistine	Sulfamethoxazole	Tetracicline
Spain	170	4.7	35.3	77.1	2.9	2.9	44.7	0.6	63.5	88.8
Portugal	142	2.8	44.4	59.9	3.5	3.5	21.1	2.1	68.3	89.4
Greece	170	9.4	40.6	58.8	0.6	0.6	10.0	0.6	82.4	75.9
Poland	213	3.3	13.6	46.9	1.9	1.9	16.0	0	57.7	58.2
Germany	227	1.3	9.7	29.1	2.2	1.3	6.6	0.4	30.0	36.6
Sweden	140	0	5.7	18.6	0	0	0	0	20.7	9.3
Finland	175	0	0.6	8.6	0	0	0	0	12	18.8
On average in EU (28 member countries)	4205	2.7	18.0	38.5	1.4	1.3	10.6	0.3	42.4	52.1

Selected genes and clusters of genes encoding multidrug resistance of bacteria found in animals

No.	Genes	Clustered in:	Examples of bacteria / host	Resistance to:
1.	blaZ; bla_ARL	blaZ-blaI-blar1 operon in Tn552transposome	S. aureus, CoNS/ many species of animals	many groups of β-lactam antibiotics
2.	mec A, mecC	SCCmec	MRSA, MRSP/ many species of animals	β-laktams
3.	tet(L), tet(M), aadD, dfrK, vga (A) (ΔblaZ (functionally inactive)	pSWS47, tet (M) part of Tn916 in pSWS47	S. epidermidis/cat	tetracyclines (except glycylcyclines), kanamycin, neomycin, tobramycin, trimethoprim, lincosamides, pleuromutiline, streptogramin
4.	aacA-aphD, aadE, erm(B), tet(L), spw, lsa(E), lnu(B), ΔblaZ	pV7037	S. aureus/pigs	gentamicin, kanamycin, tobramycin, streptomycin, macrolides, lincosamides, streptogramin A and B tetracyclines, aminocyclitols, pleuromutilins
5.	aadD, erm(B), tet(L), dfrk, apmA,	pAFS11	S. aureus/cattle	kanamycin, neomycin, tobramycin, lincosamides, streptogramin B, tetracyclines (except minocycline and glycylcycline), trimethoprim, apramycin
6.	cfr, lsa(B), erm(33) spc	pSCFS1	S. sciuri/cattle	phenicols, lincosamides, oxazolidinones, pleuro- mutilines, streprogramin A and B, macrolides, aminocyclitols
7.	cfr, erm(A)	pMSA16	S. aureus/cattle	phenicols, lincosamides, oxazolidinones, pleuromutilins, streptogramin A and B, macrolides
8.	aadD, tet(L), dfrK, vga(C)	pKKS825	S. aureus/pigs	kanamycin, neomycin, tobramycin, tetracyclines (except minocycline and glycylcyclines), trimtro- prim, lycosamides, pleuromutiline, treptogramin A
9.	cfr bla_CTX-M-14b	pGXEC3	E. coli/pigs	phenicols, lincosamides, oxazolidinones, pleuromutilins, streptogramin A and B, penicillin, cephalosporins (except cefamycins), monobactams
10.	cfr, floR, tet(A)-tetR, strA/strB and sul2	pSCEC2	E. coli/ pigs	phenicols, lincosamides, oxazolidinones, pleuro- mutilines, streptogramin A and B, tetracyclines and glycylcyclins, streptomycin, and sufonamides
11.	^mcr-1, bla_CTx-M-64’ fosA3, floA3	pNH6DS2	E. coli/dogs	colistin, penicillins, cephalosporins (except cefamycins), monobactams, fosfomycin, phenicols
12.	bla_TEM-1’, aacC2, tetA, floR, strAB, rmtB, dfrA	pEC008	E. coli/poultry	penicillins, cephalosporins, aminogicosides, tetracyclines and glycylcyclines, phenicols, streptomycin, trimethoprim

Antibiotic Resistance Of Bacteria A Growing Threat For Animals And Public Health

Figures & Tables

Percentage of commensal Escherichia coli strains resistant to selected antimicrobials, isolated from fattening pigs

Selected genes and clusters of genes encoding multidrug resistance of bacteria found in animals

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